Research Question: In individuals with multiple sclerosis, does vitamin D supplementation, compared to placebo, result in a reduction in disease progression over a 12-month period?

1.   how you are defining the purpose of your project. Who is the targeted population, location and facility. What would be the result of your project being implemented? What are some possible barriers?


Select of one of the papers/the clinical trial you have found related to your practicum topic and, following the process outlined in the video lecture, conduct your appraisal. Submit your work as a word document attached to this discussion board, Answer the following questions related to each section of the paper. After you have answered each question, indicate if you conclude the trial is strong enough to include in your review for the practicum.

Title:

  1. Does the title clearly communicate the study’s content?
  2. Is the title free from sensationalism?

Introduction:

  1. Have the authors reviewed relevant background literature?
  2. Is the trial original?
  3. What clinical question is the trial addressing?
  4. Is the clinical question expressed in the PICOT format?

Methods:

  1. How specifically are the methods described?
  2. Who were the study subjects?
  3. How were the recruited?
  4. What were the exclusion criteria?
  5. How large was the sample size?
  6. Was the sample size calculated ahead of time?
  7. Was the trial controlled and what was the control?
  8. Was the trial randomized and how was randomization performed?
  9. Did the trial use allocation concealment?
  10. Was the trial blinded?
  11. What were the endpoints or outcomes?
  12. Were the results analyzed according to intention to treat or per protocol?

Results

  1. How good was the randomization?
  2. What were the results?
  3. What was the dropout rate in each group?
  4. Do the figures accurately represent the data?

Discussion: 

  1. Do the conclusions follow logically from the results?
  2. Do the authors make comparisons to the results of similar studies?
  3. Did the authors discuss limitations of the trial.
  1. Do the conclusions follow logically from the results?
  2. Do the authors make comparisons to the results of similar studies?
  3. Did the authors discuss limitations of the trial.

Are you struggling with your paper? Let us handle it - WE ARE EXPERTS!

Whatever paper you need - we will help you write it

Get started

Starts at $9 /page

How our paper writing service works

It's very simple!

  • Fill out the order form

    Complete the order form by providing as much information as possible, and then click the submit button.

  • Choose writer

    Select your preferred writer for the project, or let us assign the best writer for you.

  • Add funds

    Allocate funds to your wallet. You can release these funds to the writer incrementally, after each section is completed and meets your expected quality.

  • Ready

    Download the finished work. Review the paper and request free edits if needed. Optionally, rate the writer and leave a review.