a comparison on the effect of storage solutions on red blood cell viability and function during extended blood storage.

January 4, 2024January 4, 2024 Discipline: Biology

For each storage solutions (E-Sol 5, PAG3M, MAP) describe the composition of it and discuss how the newer solution better than the older ones (PBS, AS-1, AS-3, etc.). While discuss about the solution, provide some papers that mention it (criterias for looking for papers are: published from 2000 to 2023, only used human red blood cells).

Then, first find papers that compare the effect of storage solutions on red blood cell viability and function (papers must published from 2000 to 2023, and only used human red blood cells). The storage solutions that should be compared are: PBS, AS-1, AS-3, AS-5, E-Sol 5, SAGM, PAGGSM, PAG3M, MAP. Discuss a few papers that do the comparison and how choosing the right storage solutions can affect RBC viability (hemolysis, ATP levels, 2,3-DGP, morphology, gas diffusion, oxidative stress, hemoglobin stability, storage duration, etc.) 

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